Filiform Porokeratotic Palmoplantar Keratoderma

Filiform Porokeratotic Palmoplantar Keratoderma Facts:

• Relatively sudden onset of multiple filiform spines on palms & soles.
• May be an acquired marker of internal malignancy.

Tags: Filiform Porokeratotic Palmoplantar Keratoderma - Keratoderma - Malignancy
Posted by Medicalchemy
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Ichthyosis Hystrix Lambert

Ichthyosis Hystrix Lambert Facts:

• Famous ichthyosis disorder, which is now extinct as a pedigree.
• Named after the family of Lamberts who were known as the porcupine men.
• The Lamberts were famous at English side shows in the 18th century.
• The spines covered the entire body except the face, palms, soles & genitalia.

Tags: Ichthyosis - Ichthyosis Hystrix Lambert - Lambert - Porcupine Men -
Posted by Medicalchemy
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Sporotrichoid Skin Lesions

Sporotrichoid Skin Lesions Differential Diagnosis:

• Anthrax
• Atypical mycobacterial infection
• Cat Scratch Disease
• Nocardiosis
• Sporotrichosis
• Tuberculosis
• Tularemia

Tags: Anthrax - Cat Scratch Disease - Nocardiosis - Sporotrichoid Skin Lesions - Sporotrichosis - TB - Tularemia
Posted by Medicalchemy
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Plantar Fibromatosis

Plantar Fibromatosis Facts:

• Synon - Ledderhose Disease, Fibromatosis Plantans
• Similar to Dupuyten's contracture but involves the plantar regions.
• May be associated with joint motion contractures, esp the big toe.
• Treatment is similar to that with Dupuytren's contracture, ie surgical excision is the best option.

Tags: Dupuytren's Contracture - Plantar Fibromatosis -
Posted by Medicalchemy
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Acneiform Drug Reactions

Acneiform Drug Reactions:

• Most common sites are - face, chest & back.
• Monomorphous exanthem which arises rapidly.
• Relatively few comedones are present.

Drugs associated:

• Androgens
• Barbiturates
• Corticosteroids (common)
• Cyclosporin
• Disulfiram
• Ethionamide
• Halides
• Isoniazid
• Lithium (common)
• Oral contraceptives
• Phenytoin (common)
• PUVA
• Rifampicin
• Tetracyclines
• Vitamin B2
• Vitamin B6
• Vitamin B12

Differential Diagnosis:

• Bacterial folliculitis
• Eosinophilic pustulosis (immunosuppressed)
• Pityrosporum folliculitis

Tags: Acneiform Drug Reaction - Bacterial folliculitis - Eosinophilic pustulosis - Pityrosporum folliculitis
Posted by Medicalchemy
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Lichen Spinulosis

Lichen Spinulosis Features:

• Also known as Spinulosismus.
• Unclear nature of the condition.
• Some define as a spiny variant of keratosis pilaris.
• Others describe it as patches (round or oval) of grouped follicular plugs.
• Associated with HIV/ AIDS - possible overlap with pityriasis rubra pilaris.

Differential Diagnosis:

• Follicular Hyperkeratotic Spicules
• Hyperkeratosis Follicularis et Parafollicularis in Cutem Penetrans
• Lichen scrofulosorum
• Lichenoid fungal id reaction (lichen trichophyticus)
• Punctate porokeratosis

Tags: Lichen Spinulosis - Keratosis - Pityriasis Rubra Pilaris
Posted by Medicalchemy
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